Episode 592 with Jon Stringer!

Comedian Jon Stringer (@jonjstringer) joins Andy, Jesse and Matt to talk about living in a converted rural Kansas church, the intricacies of comedy competitions and cruise ship comedy, dry ice PVC soupcan launchers, the oldest known use of poison arrows, retail blowguns and their misuse, vibe-coding a band manager, why you should stop using hydrogen peroxide on cuts, sword canes and pendulous doorknockers.

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Episode 591 with Imaan Hadchiti!

Comedian Imaan Hadchiti (@imaanfrankhadchiti) joins Jesse, Andy and Matt to talk about Rima syndrome, the movie Tiptoes, the passing of an art legend, sniffing farts to prevent Alzheimer's, what actually causes ice to be slippery, when physical aging really kicks in and making paralyzed rats walk again in a really creepy way.

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Episode 590 with Waen Shepherd!

Comedian/actor/writer/composer Waen Shepherd (@waenshep) joins Andy, Jesse and Matt to talk about the new album from his alter ego Gary Le Strange, the biology of elves, the best chocolate chip cookie recipe, a runaway supermassive black hole, a lemon-shaped exoplanet and the music of Gary Wilson.

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Episode 589 with Chris Duffy!

Comedian/host/author Chris Duffy (@chrisiduffy) returns to the show to talk with Jesse, Andy and Matt about his new book Humor Me: How Laughing More Can Make You Present, Creative, Connected, and Happy, his radio show/podcast You're The Expert, his TED podcast How To Be a Better Human, the unintentionally phallic Covid-era Terry Crews video Chris worked on with Matt and Andy, prescribing standup to improve mental health, training Swedish crows to pick up cigarette butts and a frozen worm revived after 46,000 years.

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Episode 588 with Buddy Fitzpatrick!

Comedian Buddy Fitzpatrick (@buddycomic) joins Andy, Matt and Jesse to talk about Batman's effect on subway chivalry, the rooms of Madonna Inn, ladyfingers, manmade fire from 350,000 years earlier than previously thought, monogamy across the animal kingdom and an insane chain of rabies transmission via organ transplantation.

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Episode 587 with Adam Burke!

Comedian Adam Burke (@atpburke) joins Andy, Jesse and Matt to talk about Adam's new comedy special Unamerican, debunking the Stanford Prison Experiment, classic '80s Arnold movies, Matt and Jesse performing together in Nashville, the preacher who shot an escaped lab monkey, AIs that believe themselves to be more rational than humans, 3D printing with a mosquito proboscis, Andy's upcoming orchestra shows and Matt's upcoming San Deigo standup show.

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Episode 586 with Ophira Eisenberg!

Comedian/writer/NPR host Ophira Eisenberg (@ophirae) joins Andy, Jesse and Matt to talk about her podcast Parenting Is a Joke, her upcoming special produced by Lewis Black, the effect of venting on anger, a rage room show Andy worked on, why you should leave uncontacted tribes alone, the wombat-thief influencer and why you should speak up to seagulls.

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Episode 585 with Jeff Zenisek!

Comedian Jess Zenisek (@jeffzenisek) joins Andy, Jesse and Matt to talk about tennis, homophobic sports stereotypes, Jesse's new ski persona, Mr. Wizard, Jeff's hair care regimen, a tiny tyrannosaur, a better rock-paper-scissors strategy, gray hair's relationship to cancer, the worst music to play during sex and the banger Parked By The Lake.

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Episode 584 with Drew Droege!

Comedian/playwright Drew Droege (@drew_droege) joins Matt, Jesse and Andy to talk about his new off-Broadway play Messy White Gays, X-ray NBA poker fraud and why birds sing after a solar eclipse.

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Episode 583 with Mehran Khaghani!

Wonderful NY comic Mehran Khagani (@themehran) joins Jesse and Matt to talk about escaping from Iran, working at the Harvard School of Public Health, hyrax butt drag fossil marks, Canadian heart transplants and the most pristine star in the universe.

In the Patreon bonus ep we get into penguin micronaps.

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Episode 582 with Jen Kober!

Comedian/actor Jen Kober (@jenkober) joins Andy, Jesse and Matt to talk about comedy in Louisiana, Oktoberfest, buxom wenches, the connection between fish buttholes and fingers, a koala chlamydia vaccine, Jesse's newfound raccoon fame, light-powered gears that fit inside a strand of hair and Jen's membership in the Star Wars canon.

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Episode 581 with NASA Exoplanet Science Ambassador Anjali Tripathi!

NASA astrophysicist and JPL Exoplanet Science Ambassador Anjali Tripathi joins Andy, Jesse and Matt to talk about exoplanets and the different ways of finding them including radial velocity, transits and gravitational microlensing, the challenges of studying planetary atmospheres, why telescopes are built in deserts or in space, Anjali's time at the White House Office of Science and Technology Policy, science communication projects like the Logic 44ever rap video, the upcoming Nancy Grace Roman Space Telescope, dark matter, lasers in astronomy, Halloween at the White House, the odd “smells” of other planets and how to take a virtual tour of JPL.

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Episode 580 with Michelle Murphy!

Comedian Michelle Murphy (@meeshoffleash) joins Andy, Matt and Jesse to talk about playing tennis for Grinnell, the Enhanced Games, celebrities trying their hands at winter sports, Jesse's accidental mermaid book purchase and the Dr. Seuss book he was aiming for, Burning Man missionaries, LSD to fight anxiety and surprisingly not too uncommon iridescent mammals.

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Episode 579 with Ken Reid!

Comedian Ken Reid (@kennethwreid) joins Jesse, Matt and Andy to talk about growing up a child of television, mud wrestling, Ken's podcast TV Guidance Counselor, an HIV prevention breakthrough, the insanity of Movie 43, the human washing machine no one asked for, blasting plastic waste with a plasma torch, Doja Cat's nod to Max Headroom, Ladies and Gentlemen, The Fabulous Stains, the reason plastic recycling mostly ended, Andy's Oktoberfest shows in Lake Arrowhead and John Williams polka music.

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Episode 578 with Ryan O'Flanagan!

Comedian Ryan O'Flanagan (@ryanoflan) joins Matt, Jesse and Andy to talk about Ryan and Andy's chance encounter in a bar in Leadville, Married With Children tattoos, neanderthals and homo sapiens interbreeding, a novel telescope shape to help search for exoplanets, an insane impression of a neanderthal voice and Ryan's podcast Laser Show.

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Episode 577 with Myq Kaplan!

Comedian Myq Kaplan (@myqkaplan) returns to the show to talk to Andy, Jesse and Matt about growing out his eyebrows during the pandemic, babies distinguishing Ps from Bs, linguistics, sign language variations, standups aping Shane Gillis, the Mr. Beast voice, birds' preference for crapping in the air, strong link versus weak link problems, Ryan North, whether you should pay for bad art, what sequels always get wrong and Myq's great Substack.

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Episode 576 with Macey Isaacs!

Comedian and host of the SSRI’M OK podcast Macey Isaacs joins the gang to talk about a meteorite that’s older than our planet! AI and attachment theory! And some more AI nonsense before Andy’s connection quit in a fury!

In the Patreon bonus we find out why living near the ocean extends your life.

Follow Macey on instagram and check out her podcast, and her Don’t Tell special when it drops!

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Episode 575 with Matt Parker!

Comedian/mathematician/YouTuber/author Matt Parker (@standupmaths) joins Jesse, Andy and Matt to talk about his new book Love Triangle: How Trigonometry Shapes the World, his podcast A Problem Squared, his Edinburgh Fringe show Getting Triggy With It, Mathstodon, a hawk that uses traffic patterns to target prey, desire paths, Earth's leaking core, the Gibeon meteor, Matt's comedy tour dates and Andy's Colorado music dates.

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Episode 574 with Josh Gondelman!

Comedian Josh Gondelman (@joshgondelman) joins Andy and Matt to talk about his new special Positive Reinforcement, his newsletter, his wife Maris Kreizman's new book of essays, the geek/nerd/dweeb/dork Venn diagram, Nancy Kerrigan and Chris Farley, a new ass-grass fad among chimps, ass/gas/grass bumper stickers, neanderthals eating maggots and rotten meat, how surprisingly warm Uranus is and Tylenol inducing risky behavior.

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Episode 573 with Kai Humphries!

Comedian Kai Humphries (@kaihumphries) joins Matt, Andy and Jesse to talk about his new special Gallivanting, the passing of Hulk Hogan, superheating solid gold, the Air Bud cinematic universe and an enormous 80,000-year-old blob in Utah.

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